Interstellar Dust Inside and Outside the Heliosphere

In the early 1990s, after its Jupiter flyby, the Ulysses spacecraft identified interstellar dust in the solar system. Since then the in-situ dust detector on board Ulysses continuously monitored interstellar grains with masses up to 10e-13 kg, penetrating deep into the solar system. While Ulysses measured the interstellar dust stream at high ecliptic latitudes between 3 and 5 AU, interstellar impactors were also measured with the in-situ dust detectors on board Cassini, Galileo and Helios, covering a heliocentric distance range between 0.3 and 3 AU in the ecliptic plane. The interstellar dust stream in the inner solar system is altered by the solar radiation pressure force, gravitational focussing and interaction of charged grains with the time varying interplanetary magnetic field. The grains act as tracers of the physical conditions in the local interstellar cloud (LIC). Our in-situ measurements imply the existence of a population of 'big' interstellar grains (up to 10e-13 kg) and a gas-to-dust-mass ratio in the LIC which is a factor of > 2 larger than the one derived from astronomical observations, indicating a concentration of interstellar dust in the very local interstellar medium. Until 2004, the interstellar dust flow direction measured by Ulysses was close to the mean apex of the Sun's motion through the LIC, while in 2005, the data showed a 30 deg shift, the reason of which is presently unknown. We review the results from spacecraft-based in-situ interstellar dust measurements in the solar system and their implications for the physical and chemical state of the LIC.Comment: 10 pages, 2 b/w figures, 1 colour figure; submitted to Space Science Review

Aspects of the Mass Distribution of Interstellar Dust Grains in the Solar System from In-Situ Measurements

The in-situ detection of interstellar dust grains in the Solar System by the dust instruments on-board the Ulysses and Galileo spacecraft as well as the recent measurements of hyperbolic radar meteors give information on the properties of the interstellar solid particle population in the solar vicinity. Especially the distribution of grain masses is indicative of growth and destruction mechanisms that govern the grain evolution in the interstellar medium. The mass of an impacting dust grain is derived from its impact velocity and the amount of plasma generated by the impact. Because the initial velocity and the dynamics of interstellar particles in the Solar System are well known, we use an approximated theoretical instead of the measured impact velocity to derive the mass of interstellar grains from the Ulysses and Galileo in-situ data. The revised mass distributions are steeper and thus contain less large grains than the ones that use measured impact velocities, but large grains still contribute significantly to the overall mass of the detected grains. The flux of interstellar grains with masses $> 10^{-14} {\rm kg}$ is determined to be $1\cdot 10^{-6} {\rm m}^{-2} {\rm s}^{-1}$. The comparison of radar data with the extrapolation of the Ulysses and Galileo mass distribution indicates that the very large ($m > 10^{-10} {\rm kg}$) hyperbolic meteoroids detected by the radar are not kinematically related to the interstellar dust population detected by the spacecraft.Comment: 14 pages, 11 figures, to appear in JG

Galileo dust data from the jovian system: 2000 to 2003

The Galileo spacecraft was orbiting Jupiter between Dec 1995 and Sep 2003. The Galileo dust detector monitored the jovian dust environment between about 2 and 370 R_J (jovian radius R_J = 71492 km). We present data from the Galileo dust instrument for the period January 2000 to September 2003. We report on the data of 5389 particles measured between 2000 and the end of the mission in 2003. The majority of the 21250 particles for which the full set of measured impact parameters (impact time, impact direction, charge rise times, charge amplitudes, etc.) was transmitted to Earth were tiny grains (about 10 nm in radius), most of them originating from Jupiter's innermost Galilean moon Io. Their impact rates frequently exceeded 10 min^-1. Surprisingly large impact rates up to 100 min^-1 occurred in Aug/Sep 2000 when Galileo was at about 280 R_J from Jupiter. This peak in dust emission appears to coincide with strong changes in the release of neutral gas from the Io torus. Strong variability in the Io dust flux was measured on timescales of days to weeks, indicating large variations in the dust release from Io or the Io torus or both on such short timescales. Galileo has detected a large number of bigger micron-sized particles mostly in the region between the Galilean moons. A surprisingly large number of such bigger grains was measured in March 2003 within a 4-day interval when Galileo was outside Jupiter's magnetosphere at approximately 350 R_J jovicentric distance. Two passages of Jupiter's gossamer rings in 2002 and 2003 provided the first actual comparison of in-situ dust data from a planetary ring with the results inferred from inverting optical images.Comment: 59 pages, 13 figures, 6 tables, submitted to Planetary and Space Scienc

One year of Galileo dust data from the Jovian system: 1996

The dust detector system onboard Galileo records dust impacts in circumjovian space since the spacecraft has been injected into a bound orbit about Jupiter in December 1995. This is the sixth in a series of papers dedicated to presenting Galileo and Ulysses dust data. We present data from the Galileo dust instrument for the period January to December 1996 when the spacecraft completed four orbits about Jupiter (G1, G2, C3 and E4). Data were obtained as high resolution realtime science data or recorded data during a time period of 100 days, or via memory read-outs during the remaining times. Because the data transmission rate of the spacecraft is very low, the complete data set (i. e. all parameters measured by the instrument during impact of a dust particle) for only 2% (5353) of all particles detected could be transmitted to Earth; the other particles were only counted. Together with the data for 2883 particles detected during Galileo's interplanetary cruise and published earlier, complete data of 8236 particles detected by the Galileo dust instrument from 1989 to 1996 are now available. The majority of particles detected are tiny grains (about 10 nm in radius) originating from Jupiter's innermost Galilean moon Io. These grains have been detected throughout the Jovian system and the highest impact rates exceeded $\rm 100 min^{-1}$. A small number of grains has been detected in the close vicinity of the Galilean moons Europa, Ganymede and Callisto which belong to impact-generated dust clouds formed by (mostly submicrometer sized) ejecta from the surfaces of the moons (Kr\"uger et al., Nature, 399, 558, 1999). Impacts of submicrometer to micrometer sized grains have been detected thoughout the Jovian system and especially in the region between the Galilean moons.Comment: accepted for Planetary and Space Science, 33 pages, 6 tables, 10 figure

Bringing Open Data to Whole Slide Imaging

Supplementary information associated with Besson et al. (2019) ECDP 2019 Faced with the need to support a growing number of whole slide imaging (WSI) file formats, our team has extended a long-standing community file format (OME-TIFF) for use in digital pathology. The format makes use of the core TIFF specification to store multi-resolution (or "pyramidal") representations of a single slide in a flexible, performant manner. Here we describe the structure of this format, its performance characteristics, as well as an open-source library support for reading and writing pyramidal OME-TIFFs

Four years of Ulysses dust data: 1996 to 1999

The Ulysses spacecraft is orbiting the Sun on a highly inclined ellipse ($i = 79^{\circ}$, perihelion distance 1.3 AU, aphelion distance 5.4 AU). Between January 1996 and December 1999 the spacecraft was beyond 3 AU from the Sun and crossed the ecliptic plane at aphelion in May 1998. In this four-year period 218 dust impacts were recorded with the dust detector on board. We publish and analyse the complete data set of both raw and reduced data for particles with masses $\rm 10^{-16} g$ to $\rm 10^{-8}$ g. Together with 1477 dust impacts recorded between launch of Ulysses and the end of 1995 published earlier \cite{gruen1995c,krueger1999b}, a data set of 1695 dust impacts detected with the Ulysses sensor between October 1990 and December 1999 is now available. The impact rate measured between 1996 and 1999 was relatively constant with about 0.2 impacts per day. The impact direction of the majority of the impacts is compatible with particles of interstellar origin, the rest are most likely interplanetary particles. The observed impact rate is compared with a model for the flux of interstellar dust particles. The flux of particles several micrometers in size is compared with the measurements of the dust instruments on board Pioneer 10 and Pioneer 11 beyond 3 AU (Humes 1980, JGR, 85, 5841--5852, 1980). Between 3 and 5 AU, Pioneer results predict that Ulysses should have seen five times more ($\rm \sim 10 \mu m$ sized) particles than actually detected.Comment: accepted by Planetary and Space Science, 22 pages, 8 figures (1 colour figure

A call for public archives for biological image data

Public data archives are the backbone of modern biological and biomedical research. While archives for biological molecules and structures are well-established, resources for imaging data do not yet cover the full range of spatial and temporal scales or application domains used by the scientific community. In the last few years, the technical barriers to building such resources have been solved and the first examples of scientific outputs from public image data resources, often through linkage to existing molecular resources, have been published. Using the successes of existing biomolecular resources as a guide, we present the rationale and principles for the construction of image data archives and databases that will be the foundation of the next revolution in biological and biomedical informatics and discovery.Comment: 13 pages, 1 figur

TrakEM2 Software for Neural Circuit Reconstruction

A key challenge in neuroscience is the expeditious reconstruction of neuronal circuits. For model systems such as Drosophila and C. elegans, the limiting step is no longer the acquisition of imagery but the extraction of the circuit from images. For this purpose, we designed a software application, TrakEM2, that addresses the systematic reconstruction of neuronal circuits from large electron microscopical and optical image volumes. We address the challenges of image volume composition from individual, deformed images; of the reconstruction of neuronal arbors and annotation of synapses with fast manual and semi-automatic methods; and the management of large collections of both images and annotations. The output is a neural circuit of 3d arbors and synapses, encoded in NeuroML and other formats, ready for analysis